E1021K Homozygous Mutation in PIK3CD Leads to Activated PI3K-Delta Syndrome 1

Absence of Tumor Necrosis Factor Supports Alternative Activation of Macrophages in the Liver after Infection with Leishmania major

Shanshan Hu, Cameron Marshall, Jocelyn M. Darby et al. · Frontiers in Immunology · 2018 · 983 citations · Full text

Veterinary Medicine, Immunology, Pathology +17

Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency

C. Lucas, Hye Sun Kuehn, Fang Zhao et al. · Nature Immunology · 2013 · 664 citations

Life Sciences, Genetics, Immunology +15

Phosphoinositide 3-Kinase δ Gene Mutation Predisposes to Respiratory Infection and Airway Damage

Ivan L. Ângulo, Oscar Vadas, Fabien Garçon et al. · Science · 2013 · 623 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Immunoglobulin Analysis Tool: A Novel Tool for the Analysis of Human and Mouse Heavy and Light Chain Transcripts

Tobias Rogosch, Sebastian Kerzel, Kam Hon Hoi et al. · Frontiers in Immunology · 2012 · 555 citations · Full text

Life Sciences, Bioinformatics, Immunology +17

Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study

Tanya Coulter, Anita Chandra, Chris M. Bacon et al. · Journal of Allergy and Clinical Immunology · 2016 · 450 citations · Full text

Medicine, Immunology, Pediatrics +15