Concepedia

Activation of Tyrosine Metabolism in CD13+ Cancer Stem Cells Drives Relapse in Hepatocellular Carcinoma

Li Sun, Lin Zhang, Jun Chen, Chaoqun Li, Hongqin Sun, Jiangrong Wang, Hong Xiao

Cancer Research and Treatment · 2019 · 49 citations · 15 references

DOIFull text

Open access

Abstract

These findings encourage further exploration of eliminating CD13+ cells by targeting specific metabolic pathways to prevent recurrence in HCCs.

References

15

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram et al. · CA A Cancer Journal for Clinicians · 2018 · 86.6K citations · Full text

Management of Hepatocellular Carcinoma: An Update Δσ

Jordi Bruix, Morris Sherman · Hepatology · 2011 · 8.1K citations · Full text

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

Richard Possemato, Kevin M. Marks, Yoav D. Shaul et al. · Nature · 2011 · 1.7K citations · Full text

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Identification and Characterization of Tumorigenic Liver Cancer Stem/Progenitor Cells

Stephanie Ma, Kwok‐Wah Chan, Liang Hu et al. · Gastroenterology · 2007 · 1.2K citations · Full text

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The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse

Anna Merlos‐Suárez, Francisco M. Barriga, Peter Jung et al. · Cell stem cell · 2011 · 928 citations · Full text

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