Novel glucagon- and OXM-based peptides acting through glucagon and GLP-1 receptors with body weight reduction and anti-diabetic properties

Effects of Exenatide (Exendin-4) on Glycemic Control and Weight Over 30 Weeks in Metformin-Treated Patients With Type 2 Diabetes

Ralph A. DeFronzo, Robert E. Ratner, Jenny Han et al. · Diabetes Care · 2005 · 1.6K citations

Medicine, Endocrinology, Pharmacology +11

Effects of Exenatide (Exendin-4) on Glycemic Control Over 30 Weeks in Patients With Type 2 Diabetes Treated With Metformin and a Sulfonylurea

David M. Kendall, Matthew C. Riddle, Julio Rosenstock et al. · Diabetes Care · 2005 · 1.2K citations · Full text

Medicine, Endocrinology, Pharmacology +17

Dipeptidyl‐peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon‐like peptide‐1(7–36)amide, peptide histidine methionine and is responsible for their degradation in human serum

Rolf Mentlein, Baptist Gallwitz, Wolfgang E. Schmidt · European Journal of Biochemistry · 1993 · 1.2K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1·8 million participants

The Lancet · 2013 · 1.1K citations · Full text

Medicine, Cardiology, Nutrition +14

Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas.

John Eng, Wayne Kleinman, L Singh et al. · Journal of Biological Chemistry · 1992 · 984 citations · Full text

Life Sciences, Biochemistry, Pharmacology +11