Up-regulation of PTEN via LPS/AP-1/NF-κB pathway inhibits trophoblast invasion contributing to preeclampsia

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 181.5K citations

Life Sciences, Molecular Biology, Molecular Genetics +9

Pten Dose Dictates Cancer Progression in the Prostate

Lloyd C. Trotman, Masaru Niki, Zohar Dotan et al. · PLoS Biology · 2003 · 668 citations · Full text

Medicine, Genetics, Oncology +15

Subtle variations in Pten dose determine cancer susceptibility

Andrea Alimonti, Arkaitz Carracedo, John G. Clohessy et al. · Nature Genetics · 2010 · 580 citations · Full text

Medicine, Cancer Biology, Oncology +4

Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway

Yu-Ru Lee, Ming Chen, Jonathan D. Lee et al. · Science · 2019 · 340 citations

Medicine, Molecular Biology, Oncology +17

Loss of PTEN induces lung fibrosis via alveolar epithelial cell senescence depending on NF‐κB activation

Yaqiong Tian, Hui Li, Ting Qiu et al. · Aging Cell · 2018 · 205 citations · Full text

Education, Cell Biology, Molecular Medicine +17