Subtle variations in Pten dose determine cancer susceptibility

Pten is essential for embryonic development and tumour suppression

Antonio Di Cristofano, Bárbara Pesce, Carlos Cordon‐Cardo et al. · Nature Genetics · 1998 · 1.5K citations

Life Sciences, Developmental Biology, Molecular Genetics +14

Tenets of PTEN Tumor Suppression

Leonardo Salmena, Arkaitz Carracedo, Pier Paolo Pandolfi · Cell · 2008 · 1K citations · Full text

Medicine, Cancer Biology, Oncology +12

Mutation of <i>Pten/Mmac1</i> in mice causes neoplasia in multiple organ systems

Katrina Podsypanina, Lora H. Ellenson, Adriana Nemes et al. · Proceedings of the National Academy of Sciences · 1999 · 949 citations · Full text

Veterinary Medicine, Oncology, Pathology +17

<i>PIK3CA</i> Mutations Correlate with Hormone Receptors, Node Metastasis, and ERBB2, and Are Mutually Exclusive with PTEN Loss in Human Breast Carcinoma

Lao H. Saal, Karolina Holm, Matthew Maurer et al. · Cancer Research · 2005 · 886 citations

Medicine, Molecular Biology, Oncology +17

X chromosomal abnormalities in basal-like human breast cancer

Andrea L. Richardson, Zhigang C. Wang, Arcangela De Nicolo et al. · Cancer Cell · 2006 · 885 citations · Full text

Life Sciences, Genetics, Oncology +14