Concepedia

C6–O-alkylated 7-deazainosine nucleoside analogues: Discovery of potent and selective anti-sleeping sickness agents

Fabian Hulpia, Jakob Bouton, Gustavo D. Campagnaro, Ibrahim A. Alfayez, Dorien Mabille, Louis Maes, Harry P. de Koning, Guy Caljon, Serge Van Calenbergh

European Journal of Medicinal Chemistry · 2020 · 38 citations · 55 references

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55

Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors

Wenyu Yu, Emma J. Chory, Amy K. Wernimont et al. · Nature Communications · 2012 · 286 citations · Full text

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Oral fexinidazole for late-stage African Trypanosoma brucei gambiense trypanosomiasis: a pivotal multicentre, randomised, non-inferiority trial

Victor Kande Betu Ku Mesu, Wilfried Mutombo Kalonji, Clélia Bardonneau et al. · The Lancet · 2017 · 269 citations

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New Compound Sets Identified from High Throughput Phenotypic Screening Against Three Kinetoplastid Parasites: An Open Resource

Imanol Peña, Marlene Manzano, Juan Cantizani et al. · Scientific Reports · 2015 · 258 citations · Full text

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Mechanisms of Arsenical and Diamidine Uptake and Resistance in <i>Trypanosoma brucei</i>

Enock Matovu, Mhairi Stewart, Federico Geiser et al. · Eukaryotic Cell · 2003 · 210 citations · Full text

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Uptake of Diamidine Drugs by the P2 Nucleoside Transporter in Melarsen-sensitive and -resistant Trypanosoma brucei brucei

Nicola S. Carter, Bradley J. Berger, Alan H. Fairlamb · Journal of Biological Chemistry · 1995 · 208 citations · Full text

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