Fabian Hulpia

Report on a novel emerging class of highly potent benzimidazole NPS opioids: Chemical and in vitro functional characterization of isotonitazene

Peter Blanckaert, Annelies Cannaert, Katleen Van Uytfanghe et al. · Drug Testing and Analysis · 2019 · 111 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Combining tubercidin and cordycepin scaffolds results in highly active candidates to treat late-stage sleeping sickness

Fabian Hulpia, Dorien Mabille, Gustavo D. Campagnaro et al. · Nature Communications · 2019 · 76 citations · Full text

Veterinary Medicine, Medicinal Chemistry, Pharmacology +16

Revisiting tubercidin against kinetoplastid parasites: Aromatic substitutions at position 7 improve activity and reduce toxicity

Fabian Hulpia, Gustavo D. Campagnaro, Mirko Scortichini et al. · European Journal of Medicinal Chemistry · 2018 · 51 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei

Ali Al-Ghamdi, Jane C. Munday, Gustavo D. Campagnaro et al. · eLife · 2020 · 46 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +16

Discovery of Novel 7-Aryl 7-Deazapurine 3′-Deoxy-ribofuranosyl Nucleosides with Potent Activity against <i>Trypanosoma cruzi</i>

Fabian Hulpia, Kristof Van Hecke, Cristiane França da Silva et al. · Journal of Medicinal Chemistry · 2018 · 45 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13