Concepedia

miR-30-5p-mediated ferroptosis of trophoblasts is implicated in the pathogenesis of preeclampsia

Heng Zhang, Yue He, Jianxia Wang, Minghua Chen, Jianjuan Xu, Minhui Jiang, Yaling Feng, Yanfang Gu

Redox Biology · 2019 · 245 citations · 29 references

DOIFull text

Open access

Concepts

Abstract

. Inhibition of miR-30b-5p expression and supplementation with ferroptosis inhibitors attenuated the PE symptoms in rat models, making miR-30b-5p a potential therapeutic target for PE.

References

29

Glutaminolysis and Transferrin Regulate Ferroptosis

Minghui Gao, Prashant Monian, Nosirudeen Quadri et al. · Molecular Cell · 2015 · 2K citations · Full text

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Synchronized renal tubular cell death involves ferroptosis

Andreas Linkermann, Rachid Skouta, Nina Himmerkus et al. · Proceedings of the National Academy of Sciences · 2014 · 1.1K citations · Full text

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Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion

Li Yang, Dongcheng Feng, Zhanyu Wang et al. · Cell Death and Differentiation · 2019 · 877 citations · Full text

, , +12

Inhibition of neuronal ferroptosis protects hemorrhagic brain

Qian Li, Xiaoning Han, Xi Lan et al. · JCI Insight · 2017 · 708 citations · Full text

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ATF4 promotes angiogenesis and neuronal cell death and confers ferroptosis in a xCT-dependent manner

D Chen, Zheng Fan, Manfred Rauh et al. · Oncogene · 2017 · 420 citations · Full text

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