Concepedia

CFTR: New insights into structure and function and implications for modulation by small molecules

Bertrand Kleizen, J.F. Hunt, Isabelle Callebaut, Tzyh‐Chang Hwang, Isabelle Sermet‐Gaudelus, Sylvia Hafkemeyer, David N. Sheppard

Journal of Cystic Fibrosis · 2019 · 20 citations · 42 references

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References

42

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

John R. Riordan, Johanna M. Rommens, Bat-Sheva Kerem et al. · Science · 1989 · 7.4K citations

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A CFTR Potentiator in Patients with Cystic Fibrosis and the <i>G551D</i> Mutation

Bonnie W. Ramsey, Jane C. Davies, Noel G. McElvaney et al. · New England Journal of Medicine · 2011 · 2.2K citations · Full text

, , +8

Lumacaftor–Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del<i>CFTR</i>

Claire Wainwright, J.S. Elborn, Bonnie W. Ramsey et al. · New England Journal of Medicine · 2015 · 1.6K citations · Full text

, , +15

Structure of a bacterial multidrug ABC transporter

Roger Dawson, Kaspar P. Locher · Nature · 2006 · 1.3K citations

, , +11

Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

Fredrick Van Goor, Sabine Hadidaꝉ, Peter D. J. Grootenhuis et al. · Proceedings of the National Academy of Sciences · 2009 · 1.2K citations · Full text

, , +17