Concepedia

Conformational Changes On Binding

Conformational Changes On Binding is a biophysical phenomenon in which a biomolecule undergoes structural rearrangements upon ligand interaction, distinguished from mere binding events by the induction of dynamic alterations in the molecule's three-dimensional conformation that can influence binding affinity, specificity, and functional outcomes.

556

Publications

32K

Citations

2.4K

Authors

742

Institutions

Publications per year

2017–2026

90

Parents

Publications

556

Harnessing protein folding neural networks for peptide–protein docking

Tomer Tsaban, Julia K. Varga, Orly Avraham et al. · Nature Communications · 2022 · 1.2K citations · Full text

, , +17

Induced fit, conformational selection and independent dynamic segments: an extended view of binding events

Péter Csermely, Robin Palotai, Ruth Nussinov · Trends in Biochemical Sciences · 2010 · 820 citations · Full text

, , +17

Wind-Driven Currents in a Baroclinic Ocean; with Application to the Equatorial Currents of the Eastern Pacific

Harald Sverdrup · Proceedings of the National Academy of Sciences · 1947 · 736 citations · Full text

, , +17

Interaction with the NMDA receptor locks CaMKII in an active conformation

K. Ulrich Bayer, Paul De Koninck, A. Soren Leonard et al. · Nature · 2001 · 732 citations

, , +14

Experiments with the Chemostat on Spontaneous Mutations of Bacteria

Aaron Novick, Leo Szilard · Proceedings of the National Academy of Sciences · 1950 · 730 citations · Full text

, , +17

1–5 of 556

Authors

2.4K

  1. JF
    J. Feeney

    National Institute for Medical Research, Tanzania

    5 publications · 370 citations

    5

    h-index

  2. RN
    Ruth Nussinov

    Tel Aviv University, Israel

    4 publications · 1.1K citations

    4

    h-index

  3. PS
    Pierre Sînaÿ

    École Normale Supérieure - PSL, France

    3 publications · 199 citations

    3

    h-index

  4. SB
    Stefan Becker

    Max Planck Institute for Biophysical Chemistry, Germany

    3 publications · 97 citations

    3

    h-index

  5. CW
    Corey W. Liu

    Stanford University, United States

    3 publications · 231 citations

    3

    h-index

1–5 of 2.4K

Institutions

742

  1. Centre National de la Recherche Scientifique

    Paris, France

    16 h-index

    76 publications

    3.8K citations

  2. Harvard University

    Cambridge, United States

    11 h-index

    25 publications

    1.6K citations

  3. Chinese Academy of Sciences

    Beijing, China

    10 h-index

    32 publications

    892 citations

  4. Cornell University

    Ithaca, United States

    9 h-index

    19 publications

    792 citations

  5. University of California San Diego

    San Diego, United States

    9 h-index

    17 publications

    989 citations

  6. Inserm

    Paris, France

    9 h-index

    26 publications

    1.7K citations

  7. Kyoto University

    Kyoto, Japan

    9 h-index

    23 publications

    1.1K citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    8 h-index

    19 publications

    881 citations

1–8 of 742

Venues

  1. Journal of Biological Chemistry

    JBC · 49 publications · 2.3K citations

    29

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 43 publications · 4.4K citations

    28

    h-index

  3. Journal of Molecular Biology

    JMB · 37 publications · 2.1K citations

    26

    h-index

  4. Biochemistry

    45 publications · 2.3K citations

    25

    h-index

  5. Biophysical Journal

    19 publications · 1K citations

    16

    h-index

1–5