Concepedia

Irisin increases the expression of anorexigenic and neurotrophic genes in mouse brain

Annalisa Natalicchio, Nicola Marrano, Giuseppina Biondi, Lucia Dipaola, Rosaria Spagnuolo, Angelo Cignarelli, Sebastio Perrini, Luigi Laviola, Francesco Giorgino

Diabetes/Metabolism Research and Reviews · 2019 · 31 citations · 31 references

DOI

Abstract

These results suggest that intraperitoneal injection of irisin, although without effects on feeding behaviour and body weight, can increase the expression of anorexigenic and neurotrophic genes in mouse brain.

References

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Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway

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Irisin Stimulates Browning of White Adipocytes Through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase Signaling

Yuan Zhang, Rui Li, Yan Meng et al. · Diabetes · 2013 · 717 citations · Full text