Concepedia

Synthesis and biological evaluation of novel pyrazolo[1,5-a]pyrimidines: Discovery of a selective inhibitor of JAK1 JH2 pseudokinase and VPS34

Justin D. Singleton, Reuben Dass, Nathaniel R. Neubert, Rachel M. Smith, Zak Webber, Marc D.H. Hansen, Matt A. Peterson

Bioorganic & Medicinal Chemistry Letters · 2019 · 20 citations · 53 references

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References

53

Role of AMP-activated protein kinase in mechanism of metformin action

Gaochao Zhou, Robert P. Myers, Ying Li et al. · Journal of Clinical Investigation · 2001 · 5.4K citations

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The selectivity of protein kinase inhibitors: a further update

Jenny Bain, Lorna Plater, Matt Elliott et al. · Biochemical Journal · 2007 · 2.5K citations · Full text

, , +14

A quantitative analysis of kinase inhibitor selectivity

Mazen W. Karaman, Sanna Herrgård, Daniel K. Treiber et al. · Nature Biotechnology · 2008 · 2.4K citations

, , +13

A small molecule–kinase interaction map for clinical kinase inhibitors

Miles A. Fabian, William Biggs, Daniel K. Treiber et al. · Nature Biotechnology · 2005 · 1.9K citations · Full text

, , +12

Halogen bonds in biological molecules

Pascal Auffinger, Franklin A. Hays, Éric Westhof et al. · Proceedings of the National Academy of Sciences · 2004 · 1.6K citations · Full text

, , +17