Concepedia

Exosome-Derived <i>microRNA</i>-<i>22</i> Ameliorates Pulmonary Fibrosis by Regulating Fibroblast-to-Myofibroblast Differentiation <i>in Vitro</i> and <i>in Vivo</i>

Naoyuki Kuse, Koichiro Kamio, Arata Azuma, Kuniko Matsuda, Minoru Inomata, Jiro Usuki, Akemi Morinaga, Toru Tanaka, Takeru Kashiwada, Kenichiro Atsumi,

Journal of Nippon Medical School · 2019 · 73 citations · 28 references

DOIFull text

Open access

Abstract

Exosomal miR-22 modulates fibroblast-to-myofibroblast differentiation. The present findings warrant further study, which could shed light on miR-22 as a novel therapeutic target in IPF.

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