Concepedia

Qualification of impurities based on metabolite data

Lars Weidolf, Thomas Andersson, Joel P. Bercu, Andreas Brink, Susanne Glowienke, James Harvey, Martin A. Hayes, Pascale Jacques, Chuang Lu, Nenad Manevski,

Regulatory Toxicology and Pharmacology · 2019 · 20 citations · 11 references

DOI

Concepts

References

11

Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: Role of circulating active metabolites

Bojan Lalovic, Evan D. Kharasch, Danny D. Shen · Clinical Pharmacology & Therapeutics · 2006 · 416 citations

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Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: Role of circulating active metabolites

S.E. Abram · Yearbook of Anesthesiology and Pain Management · 2007 · 318 citations

, , +10

Morphine metabolism in man

S. Fred Brunk, Margrieta Delle · Clinical Pharmacology & Therapeutics · 1974 · 231 citations

, , +14

Pioneering better science through the 3Rs: an introduction to the national centre for the replacement, refinement, and reduction of animals in research (NC3Rs).

Natalie Burden, Kathryn Chapman, Fiona Sewell et al. · PubMed · 2015 · 157 citations

, , +8

THE RELATIONSHIP BETWEEN THE METABOLISM OF RIBAVIRIN AND ITS PROPOSED MECHANISM OF ACTION

Jon P. Miller, Linda J Kigwana, David Streeter et al. · Annals of the New York Academy of Sciences · 1977 · 87 citations

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