Autophagy · 2019 · 53 citations · 44 references
Life SciencesNeurologyNeuroscienceAutophagyMolecular NeuroscienceNeurodegenerationAmyotrophic Lateral SclerosisNeurodegeneration MechanismsNeurodegenerative DiseasesNeurodegenerative DisordersProtein Aggregation DisordersProtein DegradationAmyotrophic Lateral Sclerosis PathologyNeurodegeneration PathogenesisNeurodegenerative Pathway MechanismsProteasome DysfunctionProteasome SystemTar Dna-binding Protein 43 PathologyTdp-43 PathologyUbiquitin-proteasome System Dysfunction
; cCASP3: cleaved caspase 3; CSNK2: casein kinase 2; FTLD: frontotemporal lobar degeneration; MAP1LC3/LC3: microtubule-associated protein 1 light chain 3; OPTN: optineurin; PTK2/FAK: PTK2 protein tyrosine kinase 2; SQSTM1/p62: sequestosome 1; TARDBP/TDP-43: TAR DNA binding protein; TBK1: TANK binding kinase 1; ULK1: unc-51 like autophagy activating kinase 1; UPS: ubiquitin-proteasome system.
44
Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
Manuela Neumann, Deepak M. Sampathu, Linda K. Kwong et al. · Science · 2006 · 6.6K citations
A Drosophila model of Parkinson's disease
Mel Β. Feany, Welcome Bender · Nature · 2000 · 2.1K citations