Concepedia

p300/CBP inhibitor A-485 alleviates acute liver injury by regulating macrophage activation and polarization

Jinjin Peng, Jiacheng Li, Jing Huang, Pan Xu, Heming Huang, Y. Liu, Yu Liang, Bing Zhou, Hualiang Jiang, Kaixian Chen,

Theranostics · 2019 · 96 citations · 38 references

DOIFull text

Open access

Concepts

Abstract

. Our study thus provided a novel target as well as a potential drug candidate for the treatment of liver injury and possibly for other acute inflammatory diseases.

References

38

Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks

Paul Shannon, Andrew Markiel, Owen Ozier et al. · Genome Research · 2003 · 54.3K citations · Full text

, , +17

<tt>edgeR</tt> : a Bioconductor package for differential expression analysis of digital gene expression data

Mark D. Robinson, Davis J. McCarthy, Gordon K. Smyth · Bioinformatics · 2009 · 44.5K citations · Full text

, , +14

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

Yang Liao, Gordon K. Smyth, Wei Shi · Bioinformatics · 2013 · 29.1K citations · Full text

, , +14

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

Sven Heinz, Christopher Benner, Nathanael J. Spann et al. · Molecular Cell · 2010 · 14.6K citations · Full text

, , +14

Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

Davis J. McCarthy, Yunshun Chen, Gordon K. Smyth · Nucleic Acids Research · 2012 · 5.8K citations · Full text

, , +17