Knockdown of long non-coding RNA PCAT-1 inhibits myeloma cell growth and drug resistance via p38 and JNK MAPK pathways

Xianjuan Shen, Pei Shen, Qian Yang, Qingqing Yin, Feng Wang, Hui Cong, Xudong Wang, Shaoqing Ju

Journal of Cancer · 2019 · 41 citations · 30 references

DOIFull text

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Concepts

Abstract

Objective: Both previous and recent literature showed long non-coding RNAs (lncRNAs) were crucial participants in multiple myeloma (MM) evolution. However, the dynamic regulation and mechanism of lncRNAs in MM progression was not fully understood. This study will explore the expression and effects of prostate cancer-associated ncRNA transcript 1 (PCAT-1) in MM.

References

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