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Design, synthesis and biological evaluation of homoerythrina alkaloid derivatives bearing a triazole moiety as PARP-1 inhibitors and as potential antitumor drugs

Medicinal ChemistryDerivative (Chemistry)BiochemistryMedicineNatural SciencesHomoerythrina Alkaloid DerivativesPharmacotherapyAnti-cancer AgentParp-1 InhibitorsDrug DevelopmentHeterocycle ChemistryPharmacologyPharmaceutical ChemistryTriazole MoietyDrug Discovery