Science Advances · 2019 · 47 citations · 49 references
Life SciencesMolecular BiologyNeuroscienceDevelopmental NeuroscienceEpigeneticsMolecular NeuroscienceDna MethylationEpigenetic Regulation In NeuronsEpigenetic ReprogrammingNeural DevelopmentNeural DifferentiationNeuronal DifferentiationDevelopmental Dna MethylationDna Methylation ReprogrammingNeural Development EpigeneticsNeurodevelopmental EpigeneticsNeurodevelopmental EpigenomicsNeuronal Dna MethylationNeuronal Epigenetic RegulationTranscriptional Control Of Neurodifferentiation
knockout mice, and inducible expression of NEUROD2 caused TET2-associated demethylation at its in vivo binding sites. The data suggest that the reorganization of DNA methylation in developing neurons involves NEUROD2 and TET2-mediated DNA demethylation.
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Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
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Global Epigenomic Reconfiguration During Mammalian Brain Development
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DNA-binding factors shape the mouse methylome at distal regulatory regions
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