Concepedia

Association of Circulating Vitamin D With Colorectal Cancer Depends on Vitamin D–Binding Protein Isoforms: A Pooled, Nested, Case-Control Study

David C. Gibbs, Mingyang Song, Marjorie L. McCullough, Caroline Y. Um, Roberd M. Bostick, Kana Wu, W. Dana Flanders, Edward Giovannucci, Mazda Jenab, Magritt Brustad,

JNCI Cancer Spectrum · 2019 · 19 citations · 44 references

DOIFull text

Open access

Abstract

Our results suggest that the 25(OH)D-CRC association may differ by DBP isoform, and those with a DBP2-encoding genotype linked to vitamin D insufficiency may particularly benefit from adequate 25(OH)D for CRC prevention.

References

44

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram et al. · CA A Cancer Journal for Clinicians · 2018 · 86.6K citations · Full text

Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline

Michael F. Holick, Neil Binkley, Heike A. Bischoff‐Ferrari et al. · The Journal of Clinical Endocrinology & Metabolism · 2011 · 10.2K citations · Full text

A New Initiative on Precision Medicine

Francis S. Collins, Harold Varmus · New England Journal of Medicine · 2015 · 5K citations · Full text

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European Prospective Investigation into Cancer and Nutrition (EPIC): study populations and data collection

Elio Ríboli, Nadia Slimani, Pietro Ferrari et al. · Public Health Nutrition · 2002 · 1.8K citations · Full text

Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease

JoAnn E. Manson, Nancy R. Cook, I‐Min Lee et al. · New England Journal of Medicine · 2018 · 1.6K citations · Full text