Concepedia

Plin5/p-Plin5 Guards Diabetic CMECs by Regulating FFAs Metabolism Bidirectionally

Juanni Hou, Juan Feng, Hong Zhou, Heng Zhao, Dachun Yang, De Li, Yongjian Yang, Haifeng Pei

Oxidative Medicine and Cellular Longevity · 2019 · 13 citations · 52 references

DOIFull text

Open access

Abstract

Plin5 preserves lipid balance and cell survival in diabetic CMECs by regulating FFAs metabolism bidirectionally via the states of nonphosphorylation and phosphorylation.

References

52

Lipotoxic heart disease in obese rats: Implications for human obesity

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Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria

Hong Wang, Urmilla Sreenivasan, Hong Hu et al. · Journal of Lipid Research · 2011 · 464 citations · Full text

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Unique Regulation of Adipose Triglyceride Lipase (ATGL) by Perilipin 5, a Lipid Droplet-associated Protein

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Voluntary wheel running restores endothelial function in conduit arteries of old mice: direct evidence for reduced oxidative stress, increased superoxide dismutase activity and down‐regulation of NADPH oxidase

Jessica Durrant, Douglas R. Seals, Melanie L Connell et al. · The Journal of Physiology · 2009 · 236 citations · Full text

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