House dust mites activate nociceptor–mast cell clusters to drive type 2 skin inflammation

Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

Alan D. Irvine, Ana Terron-Kwiatkowski, Yiwei Zhao et al. · Nature Genetics · 2006 · 3K citations

Medicine, Dermatology, Genetics +16

Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing

Dmitry Usoskin, Alessandro Furlan, Saiful Islam et al. · Nature Neuroscience · 2014 · 2.2K citations

Life Sciences, Molecular Biology, Neuroscience +14

Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome

Giovanni Barbara, Vincenzo Stanghellini, Roberto De Giorgio et al. · Gastroenterology · 2004 · 1.5K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Dupilumab Treatment in Adults with Moderate-to-Severe Atopic Dermatitis

Lisa A. Beck, Diamant Thaçi, Jennifer D. Hamilton et al. · New England Journal of Medicine · 2014 · 1.4K citations

Medicine, Dermatology, Immunology +13

Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions

Benjamin D. McNeil, Priyanka Pundir, Sonya Meeker et al. · Nature · 2014 · 1.3K citations

Life Sciences, Immunology, Pharmacology +14