The relative role of CYP3A4 and CYP3A5 in eplerenone metabolism

IN VITRO METABOLISM OF MIDAZOLAM, TRIAZOLAM, NIFEDIPINE, AND TESTOSTERONE BY HUMAN LIVER MICROSOMES AND RECOMBINANT CYTOCHROMES P450: ROLE OF CYP3A4 AND CYP3A5

Kiran C. Patki, Lisa L. von Moltke, David J. Greenblatt · Drug Metabolism and Disposition · 2003 · 259 citations

Medicine, Pharmacokinetics, Pharmacology +17

Contribution of CYP3A5 to the in Vitro Hepatic Clearance of Tacrolimus

Landry K. Kamdem, Frank Streit, Ulrich M. Zanger et al. · Clinical Chemistry · 2005 · 220 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Involvement of CYP3A in the Metabolism of Eplerenone in Humans and Dogs: Differential Metabolism by CYP3A4 and CYP3A5

Chyung S. Cook, Loren Berry, David H. Kim et al. · Drug Metabolism and Disposition · 2002 · 62 citations

Medicine, Biochemistry, Pharmacology +15

Tacrolimus Updated Guidelines through popPK Modeling: How to Benefit More from CYP3A Pre-emptive Genotyping Prior to Kidney Transplantation

Jean‐Baptiste Woillard, Michel Mourad, Michael Neely et al. · Frontiers in Pharmacology · 2017 · 58 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Single- and repeated-dose pharmacokinetics of eplerenone, a selective aldosterone receptor blocker, in rats

C. S. Cook, L. Zhang, Gregory B. Ames et al. · Xenobiotica · 2003 · 28 citations

Pharmacy, Pharmacokinetics, Pharmacology +12