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Discovery and biological evaluation of darolutamide derivatives as inhibitors and down-regulators of wild-type AR and the mutants

Medicinal ChemistryBiochemistryMedicineNatural SciencesRational Drug DesignDarolutamide DerivativesPharmacotherapyWild-type ArBiological EvaluationDrug DevelopmentPharmacologyInhibitory ActivityDrug DiscoveryPharmaceutical ResearchDrug Resistance