Punica granatum (pomegranate) leaves extract induces apoptosis through mitochondrial intrinsic pathway and inhibits migration and invasion in non-small cell lung cancer in vitro

Yali Li, Fangfang Yang, Weidong Zheng, +7

Biomedicine & Pharmacotherapy

Mitochondrial FunctionMedicineMitochondrial Intrinsic PathwayApoptosisPathology +9

Discovery of the first potent proteolysis targeting chimera (PROTAC) degrader of indoleamine 2,3-dioxygenase 1

Mingxing Hu, Weilin Zhou, Yijie Wang, +8

Acta Pharmaceutica Sinica B

Asymmetry of Hippocampus and Amygdala Defect in Subjective Cognitive Decline Among the Community Dwelling Chinese

Ling Yue, Tao Wang, Jingyi Wang, +6

Frontiers in Psychiatry

LncRNA HOTAIR knockdown inhibits glycolysis by regulating miR-130a-3p/HIF1A in hepatocellular carcinoma under hypoxia

Mingxing Hu, Qiang Fu, Chan Jing, +3

Biomedicine & Pharmacotherapy

Punica granatum (pomegranate) peel extract exerts potent antitumor and anti-metastasis activity in thyroid cancer

Yujue Li, Tinghong Ye, Fangfang Yang, +10

RSC Advances

Past Ten YearsEpidemiology Of CancerPathologyCancer RegistrationOncology +16

A hypoxia-specific and mitochondria-targeted anticancer theranostic agent with high selectivity for cancer cells

Mingxing Hu, Chao Yang, Yi Luo, +7

Journal of Materials Chemistry B

Protective effects of Punica granatum (pomegranate) peel extract on concanavalin A-induced autoimmune hepatitis in mice

Tingting Wang, Ruoting Men, Mingxing Hu, +5

Biomedicine & Pharmacotherapy

Autoimmune DiseaseAllergyImmunotoxicologyPeel ExtractImmunology +6

miR-29a up-regulation in AR42J cells contributes to apoptosis<i>via</i>targeting<i>TNFRSF1A</i>gene

Qiang Fu, Tao Qin, Chen Lin, +6

World Journal of Gastroenterology

Discovery of potent and selective HER2 PROTAC degrader based Tucatinib with improved efficacy against HER2 positive cancers

Mingxing Hu, Yujue Li, Jiaxuan Li, +6

European Journal of Medicinal Chemistry

MedicinePharmacologyHer2 Positive CancersImproved EfficacyAnti-cancer Agent +5

Discovery and biological evaluation of darolutamide derivatives as inhibitors and down-regulators of wild-type AR and the mutants

Jiang Yu, Peiting Zhou, Mingxing Hu, +6

European Journal of Medicinal Chemistry

Medicinal ChemistryBiochemistryMedicineNatural SciencesRational Drug Design +10