Interleukin-4 and interleukin-13 as possible therapeutic targets in systemic sclerosis

Proteome-wide Analysis and CXCL4 as a Biomarker in Systemic Sclerosis

Lenny van Bon, Alsya J. Affandi, Jasper Broen et al. · New England Journal of Medicine · 2013 · 454 citations · Full text

Life Sciences, Immunology, Molecular Biology +16

The STAT4 gene influences the genetic predisposition to systemic sclerosis phenotype

J. Broen, Roger Hesselstrand, Harold Suárez et al. · Human Molecular Genetics · 2009 · 176 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Anti-IL-4 treatment prevents dermal collagen deposition in the tight-skin mouse model of scleroderma

Christopher J. Ong, Connie H. Y. Wong, Hung‐Sia Teh et al. · European Journal of Immunology · 1998 · 154 citations · Full text

Medicine, Immunology, Pathology +17

Interleukin‐13–producing CD8+ T cells mediate dermal fibrosis in patients with systemic sclerosis

Patrizia Fuschiotti, Adriana T. Larregina, Johnan Ho et al. · Arthritis & Rheumatism · 2012 · 139 citations · Full text

Medicine, Immunology, Pathology +17

Presence of CD4+CD8+ double‐positive T cells with very high interleukin‐4 production potential in lesional skin of patients with systemic sclerosis

Yann Parel, Michel Aurrand‐Lions, A Scheja et al. · Arthritis & Rheumatism · 2007 · 139 citations · Full text

Medicine, Dermatology, Immunology +17