Concepedia

Publication | Open Access

Targeting reduced mitochondrial DNA quantity as a therapeutic approach in pediatric high-grade gliomas

DOIFull Paper Access

67

Citations

24

References

2019

Year

Han Shen, Man Yu, Maria Tsoli, Cecilia Chang, Swapna Joshi, Jie Liu, Scott Ryall, Yevgen Chornenkyy, Robert Siddaway, Cynthia Hawkins,
Neuro-Oncology

Abstract

Our results suggest metabolic alterations as an onco-requisite factor of pHGG tumorigenesis. Targeting reduced mtDNA quantity represents a promising therapeutic strategy for pHGG.

References

YearCitations

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