2019 · 13 citations · 10 references
EngineeringBioengineeringChemistryAnalytical ChemistryBiosensorsSensorsAptamer-based BiosensorsBiological SensorsBiomedical SensorsChemical SensorsElectrochemical BiosensorsElectrochemical SensorsAptamer ImmobilizationAptamer-based SensorsAptamersField-effect Transistor BiosensorsLabel-free DetectionOrganic Field-effect TransistorsOrganic Thin-film TransistorsSmall-molecule Detection
In this work we implemented low cost, organic transistors for biosensory application. The sensor is fabricated primarily at low temperatures and atmospheric pressures using additive manufacturing steps and implemented as Aptamer enhanced Organic Electrolyte Gated Field Effect Transistors (OEGFETs), for detection of vital small molecules in fluid samples. To characterize the OEGFET performance, we collected I-V transfer curves of the transistor with different electrolytic solutions, with and without immobilized aptamers.
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Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery
Larry Gold, Deborah Ayers, Jennifer Bertino et al. · PLoS ONE · 2010 · 1.7K citations · Full text