T‐type calcium channels drive the proliferation of androgen‐receptor negative prostate cancer cells

Roberto Silvestri, Perla Pucci, Erik Venalainen, Chrysanthi Matheou, Rebecca Mather, Stephen Chandler, Romina Aceto, Sushilaben H. Rigas, Yuzhuo Wang, Katja Rietdorf,

The Prostate · 2019 · 21 citations · 15 references

Abstract

Our results show that TTCCs are overexpressed in advanced forms of PCa and correlate with a poorer prognosis. TTCC inhibition reduces cell proliferation and survival, suggesting that there may be possible value in the therapeutic targeting of TTCCs in advanced PCa.

References

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