Concepedia

Safety screening in early drug discovery: An optimized assay panel

Stefanie Bendels, Caterina Bissantz, Bernhard Fasching, Grégori Gerebtzoff, Wolfgang Guba, Manfred Kansy, Jacques Migeon, Susanne Mohr, Jens‐Uwe Peters, Fabien Tillier,

Journal of Pharmacological and Toxicological Methods · 2019 · 82 citations · 7 references

DOI

Concepts

References

7

In silico toxicology protocols

Glenn J. Myatt, Ernst Ahlberg, Yumi Akahori et al. · Regulatory Toxicology and Pharmacology · 2018 · 241 citations · Full text

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Predicting ADME properties and side effects: the BioPrint approach.

Cecile M. Krejsa, Dragos Horvath, Sherri L Rogalski et al. · PubMed · 2003 · 179 citations

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Computer-aided estimation of the hERG-mediated cardiotoxicity risk of potential drug components

Eugene V. Radchenko, Yu. A. Rulev, Alexander Safanyaev et al. · Doklady Biochemistry and Biophysics · 2017 · 64 citations

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Large-Scale Predictive Drug Safety: From Structural Alerts to Biological Mechanisms

Ricard García-Serna, David Vidal, Nikita Remez et al. · Chemical Research in Toxicology · 2015 · 54 citations

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Current nonclinical testing paradigms in support of safe clinical trials: An IQ Consortium DruSafe perspective

Lynne Butler, Peggy Guzzie‐Peck, James Hartke et al. · Regulatory Toxicology and Pharmacology · 2017 · 44 citations

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