Concepedia

Metabotropic, but not allosteric, effects of neurosteroids on GABAergic inhibition depend on the phosphorylation of GABAA receptors

Manasa L. Parakala, Yihui Zhang, Amit Modgil, Jayashree Chadchankar, Thuy N. Vien, Michael A. Ackley, James Doherty, Paul Davies, Stephen J. Moss

Journal of Biological Chemistry · 2019 · 49 citations · 33 references

DOIFull text

Open access

Concepts

Abstract

R phosphorylation. We propose that this mechanism may contribute to the varying behavioral effects of NAS.

References

33

Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor

Yong Zhu, Jason E. Bond, Peter Thomas · Proceedings of the National Academy of Sciences · 2003 · 702 citations · Full text

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Extrasynaptic GABAA Receptors: Their Function in the CNS and Implications for Disease

Stephen G. Brickley, István Módy · Neuron · 2012 · 681 citations · Full text

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Selective Modulation of Tonic and Phasic Inhibitions in Dentate Gyrus Granule Cells

Zoltán Nusser, István Módy · Journal of Neurophysiology · 2002 · 483 citations

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Brexanolone (SAGE-547 injection) in post-partum depression: a randomised controlled trial

Stephen Kanes, Helen Colquhoun, Handan Gunduz‐Bruce et al. · The Lancet · 2017 · 476 citations

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Brain-Derived Neurotrophic Factor Modulates Fast Synaptic Inhibition by Regulating GABA<sub>A</sub>Receptor Phosphorylation, Activity, and Cell-Surface Stability

Jasmina N. Jovanovic, Philip Thomas, Josef T. Kittler et al. · Journal of Neuroscience · 2004 · 271 citations · Full text

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