Concepedia

Lymphangiogenesis in kidney and lymph node mediates renal inflammation and fibrosis

Guangchang Pei, Ying Yao, Qian Yang, Meng Wang, Yuxi Wang, Jianliang Wu, Pengge Wang, Yueqiang Li, Fengming Zhu, Juan Yang,

Science Advances · 2019 · 103 citations · 62 references

DOIFull text

Open access

Concepts

Abstract

cells into RDLN and spleen or inhibiting lymphangiogenesis. Elucidating the role of lymphangiogenesis in promoting intrarenal inflammation and fibrosis provides a key insight that can facilitate the development of novel therapeutic strategies to prevent progression of CKD-associated fibrosis.

References

62

CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs

Reinhold Förster, Andreas Schubel, Dagmar Breitfeld et al. · Cell · 1999 · 2.3K citations · Full text

, , +11

LYVE-1, a New Homologue of the CD44 Glycoprotein, Is a Lymph-specific Receptor for Hyaluronan

Suneale Banerji, Jian Ni, Shuxia Wang et al. · The Journal of Cell Biology · 1999 · 1.6K citations · Full text

, , +16

Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

Li Yang, Tatiana Y. Besschetnova, Craig R. Brooks et al. · Nature Medicine · 2010 · 1.3K citations · Full text

, , +14

Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C–dependent buffering mechanism

Agnes Machnik, Wolfgang Neuhofer, Jonathan Jantsch et al. · Nature Medicine · 2009 · 960 citations

, , +14

Regulation of Dendritic Cell Migration to the Draining Lymph Node

Alfonso Martin‐Fontecha, Silvia Sebastiani, Uta E. Höpken et al. · The Journal of Experimental Medicine · 2003 · 870 citations · Full text

, , +17