Case Reports in Dermatology · 2019 · 15 citations · 12 references
MedicineDermatologyInfectious DiseasesDermatopathologyMedical MicrobiologyParasitic Skin DiseaseAntifungal TherapyInfectious DermatosesNail DisordersNail PathologyNail Unit InfectionsSkin InfectionsDermatophytic OnychomycosisFluconazole TherapyFungal DermatosesFungal Skin DiseasesItraconazole TherapyNail Fungal InfectionsPhenotypic Drug Susceptibility TestingTerbinafine Therapy
Trichophyton erinacei is an emerging cause of dermatophyte infections, which are frequently isolated from hedgehogs. Nail infections from T. erinacei are rarely reported. We describe the case of a 23-year-old Thai female who had a history of systemic lupus erythematosus with lupus nephritis type III and who developed widespread skin and nail infections caused by T. erinacei that were most likely transmitted from a hedgehog. Although the patient did not demonstrate a clinical improvement or mycological cure following systemic itraconazole and fluconazole treatment, she achieved clinical and mycological cures after terbinafine therapy. A drug susceptibility test should be performed in patients with T. erinacei infections to facilitate decision-making about antifungal therapy. Here, we are the first to report a case of proximal subungual onychomycosis from a T. erinacei infection.
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