Concepedia

HPA aptamer functionalized paclitaxel-loaded PLGA nanoparticles for enhanced anticancer therapy through targeted effects and microenvironment modulation

Tao Duan, Zhuobin Xu, Fumou Sun, Yang Wang, Juan Zhang, Chen Luo, Min Wang

Biomedicine & Pharmacotherapy · 2019 · 71 citations · 24 references

DOIFull text

Open access

Concepts

Abstract

(mean ± SD; n = 10) in vivo treatment. Thus, the present study indicated that HPA is a promising target for drug delivery to TNBC cells, and nanoparticle-HPA-aptamer bioconjugates can provide new insights for TNBC treatment.

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