Materials · 2019 · 39 citations · 8 references
DentistryBioengineeringBiomedical EngineeringBiocompatibilityBiomaterialsTissue EngineeringBioactive Dental MaterialsBioactive GlassesBiocompatibility Of Dental MaterialsBiomaterials For Oral RegenerationComposite BiomaterialsDental BiomaterialsBioactive Composite MaterialsBiocompatibility Of Regenerative MaterialsBondingCell Proliferation StimulationInjectable BiomaterialsScaffold BiocompatibilityStrontium-doped Bioactive GlassesSurgical Dentistry
Bioactive glasses (BGs) are currently employed in a wide range of medical and dentistry applications by virtue of their bone-bonding ability. The incorporation of BGs into a collagen matrix may be used to combine the regenerative potential of these materials with the specific biological advantages of collagen. However, most of the collagen/BG composites reported in the literature are scaffolds and there is a lack of moldable putties or injectable systems. Here, granules of an innovative BG containing strontium and magnesium were mixed with collagen and PEG to obtain a putty (BGMS/C) suitable for dental applications. For the sake of comparison, granules of 45S5 Bioglass®, the gold standard among BGs, were used to prepare a 45S5/collagen putty. Both the composites were evaluated in vitro with respect to murine fibroblasts. The materials showed an excellent biocompatibility, making them interesting for possible applications in dentistry and reconstructive surgery. Moreover, BGMS/C seems to stimulate cell proliferation.
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Devis Bellucci, Antonella Sola, Roberta Salvatori et al. · Materials Science and Engineering C · 2016 · 98 citations · Full text
Natural Sciences, Materials Engineering, Materials Science +17
Potassium based bioactive glass for bone tissue engineering
Devis Bellucci, Valeria Cannillo, Gianluca Ciardelli et al. · Ceramics International · 2010 · 52 citations · Full text