N(9)-Substituted 2-phenyl-N(6)-benzyl-8-azaadenines: A1 adenosine receptor affinity. A comparison with the corresponding N(6)-substituted 2-phenyl-N(9)-benzyl-8-azaadenines.

Abstract

The synthesis and the assay of title compounds were accomplished. Biological results indicated the general lack of activity among the tested disubstituted compounds bearing the benzyl group on N(6) and confirmed the activity of those with this group on N(9).