Concepedia

Regioselective Sonogashira Couplings of 2,4-Dibromoquinolines. A Correction

Jason M. Nolan, Daniel L. Comins

The Journal of Organic Chemistry · 2003 · 24 citations · 11 references

DOI

Concepts

Abstract

Heteronuclear multiple bond correlation (HMBC) was used to determine the regiochemical outcome of palladium-catalyzed carbon-carbon bond formation between 2,4-dibromoquinolines and terminal acetylenes. The observed regioselectivity of these coupling reactions is opposite to that reported in the literature for analogous reactions.

References

11

A convenient synthesis of acetylenes: catalytic substitutions of acetylenic hydrogen with bromoalkenes, iodoarenes and bromopyridines

Kenkichi Sonogashira, Yasuo Tohda, Nobue Hagihara · Tetrahedron Letters · 1975 · 5.1K citations

, , +11

Advances in the directed metallation of azines and diazines (pyridines, pyrimidines, pyrazines, pyridazines, quinolines, benzodiazines and carbolines). Part 1: Metallation of pyridines, quinolines and carbolines

Florence Mongin, G. QUEGUINER · Tetrahedron · 2001 · 245 citations

, , +11

Synthesis and Antitumor Activity of 20(S)-Camptothecin Derivatives: Carbamate-Linked, Water-Soluble Derivatives of 7-Ethyl-10-hydroxycamptothecin.

Seigo Sawada, Satoru Okajima, Ritsuo Aiyama et al. · Chemical and Pharmaceutical Bulletin · 1991 · 233 citations · Full text

, , +13

A Practical Six-Step Synthesis of (<i>S</i>)-Camptothecin

Daniel L. Comins, Jason M. Nolan · Organic Letters · 2001 · 125 citations

, , +9

A convenient palladium-catalyzed coupling approach to 2,5-disubstituted pyridines

Jefferson Tilley, Sonja Zawoiski · The Journal of Organic Chemistry · 1988 · 113 citations

, , +10