Concepedia

Trifluoroacetic Acid Mediated Hydroarylation: Synthesis of Dihydrocoumarins and Dihydroquinolones.

Kelin Li, Lindsay N. Foresee, Jon A. Tunge

ChemInform · 2005 · 110 citations · 7 references

DOIFull text

Open access

Concepts

Abstract

Trifluoroacetic acid mediates the hydroarylation of alkenes\nto afford dihydrocoumarins and dihydroquinolones in good\nyield. Intermolecular hydroarylation of cinnamic acids by\nphenols is particularly facile, which leads to the conclusion\nthat previous reports of palladium-catalyzed hydroarylation\nof cinnamic acids in trifluoroacetic acid are erroneous.

References

7

Thermal, Catalytic, Regiospecific Functionalization of Alkanes

Huiyuan Chen, Sabine Schlecht, Thomas C. Semple et al. · Science · 2000 · 879 citations

, , +14

C−C Bond Formation via C−H Bond Activation:  Synthesis of the Core of Teleocidin B4

B.D. Dangel, Kamil Godula, So Won Youn et al. · Journal of the American Chemical Society · 2002 · 193 citations

, , +13

Pt(IV)-catalyzed cyclization of arene–alkyne substrates via C–H bond functionalization

Stefan J. Pastine, So Won Youn, Dalibor Sameš · Tetrahedron · 2003 · 163 citations

, , +13

Trifluoroacetic Acid-Mediated Hydroarylation:  Synthesis of Dihydrocoumarins and Dihydroquinolones

Kelin Li, Lindsay N. Hayes, Jon A. Tunge · The Journal of Organic Chemistry · 2005 · 133 citations

, , +5

Trifluoroacetic Acid Mediated Hydroarylation: Synthesis of Dihydrocoumarins and Dihydroquinolones.

Kelin Li, Lindsay N. Foresee, Jon A. Tunge · ChemInform · 2005 · 110 citations · Full text

, , +6