Concepedia

Non-Catalytic Thermal Multicomponent Assembling of Isatin, Cyclic CH-Acids and Malononitrile: An Efficient Approach to Spirooxindole Scaffold

Michaïl N. Elinson, Alexey I. Ilovaisky, Valentina M. Merkulova, Tatiana A. Zaimovskaya, G. I. Nikishin

Mendeleev Communications · 2012 · 43 citations · 16 references

DOI

Concepts

Abstract

Thermal non-catalytic reaction of isatin, cyclic CH-acids and malononitrile in water or alcohols affords substituted spirooxindoles in 90–97% yields.

References

16

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