Concepedia

Phil B. Alper

PB

20

Publications

1.8K

Citations

15

H-Index

1996

Active since

Affiliations

Genomics Institute of the Novartis Research Foundation(Current)

Scripps Research Institute

Novartis (Switzerland)

Novartis Institutes for BioMedical Research

Phil B. Alper is an author at Genomics Institute of the Novartis Research Foundation specializing in natural sciences, drug discovery, and medicine.

ORCID

Top concepts

Publications per year

1996–2023

20

Publications

20

Metal catalyzed diazo transfer for the synthesis of azides from amines

Phil B. Alper, Shang‐Cheng Hung, Chi‐Huey Wong · Tetrahedron Letters · 1996 · 351 citations

, , +6

Facile, Novel Methodology for the Synthesis of Spiro[pyrrolidin-3,3′-oxindoles]: Catalyzed Ring Expansion Reactions of Cyclopropanes by Aldimines

Phil B. Alper, Christiane Meyers, Andreas Lerchner et al. · Angewandte Chemie International Edition · 1999 · 268 citations

Discovery of Tropifexor (LJN452), a Highly Potent Non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH)

David C. Tully, Paul V. Rucker, D. CHIANELLI et al. · Journal of Medicinal Chemistry · 2017 · 224 citations · Full text

, , +20

Design and Synthesis of New Aminoglycoside Antibiotics Containing Neamine as an Optimal Core Structure:  Correlation of Antibiotic Activity with in Vitro Inhibition of Translation

William A. Greenberg, E. Scott Priestley, P.S. Sears et al. · Journal of the American Chemical Society · 1999 · 216 citations

, , +22

Probing the Specificity of Aminoglycoside−Ribosomal RNA Interactions with Designed Synthetic Analogs

Phil B. Alper, Martin Hendrix, P.S. Sears et al. · Journal of the American Chemical Society · 1998 · 189 citations

, , +18

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