Concepedia

A Convenient Synthesis of Monocationic 1-[(Cyclic Amidino)methyl]thymines

Jarosław Spychała

Synthetic Communications · 1997 · 20 citations · 14 references

DOI

Concepts

Abstract

Abstract 1-[(Cyclic amidino)methyl]thymines have been conveniently synthesized from thymine in a three-step procedure via 1-cyanomethyl- and 1-[(thiocarbamoyl) methyl]thymines. The above synthetic intermediates were obtained in good yields by improved methods.

References

14

Synthesis of chiral carbocyclic nucleosides

Alan D. Borthwick, Keith Biggadike · Tetrahedron · 1992 · 351 citations

, , +12

Nucleic acid chemistry. Improved and new synthetic procedures, methods and techniques

European Journal of Medicinal Chemistry · 1991 · 68 citations

, , +14

RANEY NICKEL HYDROGENOLYSIS OF THIOAMIDES: A NEW AMINE SYNTHESIS

Edmund C. Kornfeld · The Journal of Organic Chemistry · 1951 · 54 citations

, , +6

Nucleoside Conjugates. 15. Synthesis and Biological Activity of Anti-HIV Nucleoside Conjugates of Ether and Thioether Phospholipids

Chung Hong, Alexander Nechaev, Alan J. Kirisits et al. · Journal of Medicinal Chemistry · 1996 · 28 citations

, , +15

Adenosine deaminase inhibitors: synthesis and structure activity relationships of imidazole analogs of erythro-9-(2-hydroxy-3-nonyl)adenine

Gloria Cristalli, Alessandra Eleuteri, Palmarisa Franchetti et al. · Journal of Medicinal Chemistry · 1991 · 25 citations · Full text

, , +13