Synthesis and cytotoxicity of the acyclic (E)- and (Z)-dienediyne systems related to neocarzinostatine chromophore

The structure of neocarzinostatin chromophore possessing a novel bicyclo-[7,3,0]dodecadiyne system

Kiyoto Edo, Michinao Mizugaki, Yoshio Koide et al. · Tetrahedron Letters · 1985 · 325 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

NEOCARZINOSTATIN, AN ANTITUMOR ANTIBIOTIC OF HIGH MOLECULAR WEIGHT. ISOLATION, PHYSIOCHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITIES.

N. Ishida, Katsunori Miyazaki, Kazuaki Kumagai et al. · PubMed · 1965 · 288 citations

Medicine, Medicinal Chemistry, Pharmacology +5

A method for the regiospecific synthesis of enol triflates by enolate trapping

John E. Mc Murry, William J. Scott · Tetrahedron Letters · 1983 · 284 citations

Natural Sciences, Chemistry, Synthetic Medicinal Chemistry +3

Thermal generation of .alpha.,3-dehydrotoluene from (Z)-1,2,4-heptatrien-6-yne

Elaine Y. Kuo, Nathaniel S. Finney · Journal of the American Chemical Society · 1989 · 274 citations

Natural Sciences, Chemistry, Organic Chemistry +5

Biradical formation from acyclic conjugated eneyne-allene system related to neocarzinostatin and esperamicin-calichemicin

Ryu Nagata, Hidenori Yamanaka, Eiichi Okazaki et al. · Tetrahedron Letters · 1989 · 227 citations

Natural Sciences, Chemistry, Medicinal Chemistry +6