Biradical formation from acyclic conjugated eneyne-allene system related to neocarzinostatin and esperamicin-calichemicin

p-Benzyne. Generation as an intermediate in a thermal isomerization reaction and trapping evidence for the 1,4-benzenediyl structure

Richard R. Jones, Robert G. Bergman · Journal of the American Chemical Society · 1972 · 669 citations

Natural Sciences, Chemistry, Analytical Chemistry +5

Calichemicins, a novel family of antitumor antibiotics. 2. Chemistry and structure of calichemicin .gamma.1I

May D. Lee, T. S. DUNNE, Conway C. Chang et al. · Journal of the American Chemical Society · 1987 · 520 citations

Medicine, Medicinal Chemistry, Pharmacology +6

Calichemicins, a novel family of antitumor antibiotics. 1. Chemistry and partial structure of calichemicin .gamma.1I

May D. Lee, T. S. DUNNE, Marshall M. Siegel et al. · Journal of the American Chemical Society · 1987 · 388 citations

Medicine, Medicinal Chemistry, Pharmacology +8

The structure of neocarzinostatin chromophore possessing a novel bicyclo-[7,3,0]dodecadiyne system

Kiyoto Edo, Michinao Mizugaki, Yoshio Koide et al. · Tetrahedron Letters · 1985 · 325 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Esperamicins, a novel class of potent antitumor antibiotics. 3. Structures of esperamicins A1, A2, and A1b

Jerzy Golik, George R. Dubay, Gary S. Groenewold et al. · Journal of the American Chemical Society · 1987 · 314 citations

Pharmacy, Medicinal Chemistry, Pharmacology +5