Synthesis of enantiomerically pure cyclopropyl carbocyclic nucleosides

HIV with Reduced Sensitivity to Zidovudine (AZT) Isolated During Prolonged Therapy

B. A. Larder, G. Darby, Douglas D. Richman · Science · 1989 · 1.6K citations

Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides.

Hiroaki Mitsuya, S Broder · Proceedings of the National Academy of Sciences · 1986 · 1K citations · Full text

Normal T Cells, Immunology, Cytopathic Effect +16

PHASE I STUDIES OF 2',3'-DIDEOXYCYTIDINE IN SEVERE HUMAN IMMUNODEFICIENCY VIRUS INFECTION AS A SINGLE AGENT AND ALTERNATING WITH ZIDOVUDINE (AZT)

Robert Yarchoan · The Lancet · 1988 · 510 citations

Medicine, Human Retrovirus, Immunology +7

Synthesis of chiral carbocyclic nucleosides

Alan D. Borthwick, Keith Biggadike · Tetrahedron · 1992 · 351 citations

Organic Chemistry, Chiral Carbocyclic Nucleosides, Stereoselective Synthesis +3

Potent and selective activity of a new carbocyclic nucleoside analog (Carbovir: NSC 614846) against human immunodeficiency virus In vitro

Robert Vince, Hua Mei, Jay Brownell et al. · Biochemical and Biophysical Research Communications · 1988 · 231 citations · Full text

Medicinal Chemistry, Medicine, Immunology +12