Novel 2-aryl-naphtho[1,2-d]oxazole derivatives as potential PTP-1B inhibitors showing antihyperglycemic activities

Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient Mice

Lori D. Klaman, Olivier Boss, Odile D. Peroni et al. · Molecular and Cellular Biology · 2000 · 1.2K citations

Life Sciences, Endocrinology, Molecular Biology +17

Tyrosine Dephosphorylation and Deactivation of Insulin Receptor Substrate-1 by Protein-tyrosine Phosphatase 1B

Barry J. Goldstein, Anna Bittner-Kowalczyk, Morris F. White et al. · Journal of Biological Chemistry · 2000 · 416 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Novel Benzofuran and Benzothiophene Biphenyls as Inhibitors of Protein Tyrosine Phosphatase 1B with Antihyperglycemic Properties

Michael S. Malamas, Janet Sredy, Christopher Moxham et al. · Journal of Medicinal Chemistry · 2000 · 213 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

PTP1B Inhibition and Antihyperglycemic Activity in the ob/ob Mouse Model of Novel 11-Arylbenzo[<i>b</i>]naphtho[2,3-<i>d</i>]furans and 11-Arylbenzo[<i>b</i>]naphtho[2,3-<i>d</i>]thiophenes

Jay Wrobel, Janet Sredy, Christopher Moxham et al. · Journal of Medicinal Chemistry · 1999 · 126 citations · Full text

Medicine, Biochemistry, Pharmacology +6

Investigation of Potential Bioisosteric Replacements for the Carboxyl Groups of Peptidomimetic Inhibitors of Protein Tyrosine Phosphatase 1B:  Identification of a Tetrazole-Containing Inhibitor with Cellular Activity

Charlotta Liljebris, Scott D. Larsen, D. Ogg et al. · Journal of Medicinal Chemistry · 2002 · 108 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17