Concepedia

One-Step Synthesis of Biphenylacetic Acids via Pd/C-Catalyzed Arylation

D. GALA, Andrew W. Stamford, Jack L. Jenkins, Max Kugelman

Organic Process Research & Development · 1997 · 60 citations · 9 references

DOI

Concepts

Abstract

An efficient, convenient, one-step synthesis of biphenylacetic acids using Pd/C as a catalyst is described. This has been successfully used for the preparation of mole amounts of acids.

References

9

The Palladium-Catalyzed Cross-Coupling Reaction of Phenylboronic Acid with Haloarenes in the Presence of Bases

Norio Miyaura, Teiji Yanagi, Atsushi Suzuki · Synthetic Communications · 1981 · 1.9K citations · Full text

, , +14

Aryl couplings with heterogeneous palladium catalysts

Guy Marck, A. Villiger, Richard Buchecker · Tetrahedron Letters · 1994 · 191 citations

, , +12

Biaryl synthesis via suzuki coupling on a solid support

Richard Frenette, Richard W. Friesen · Tetrahedron Letters · 1994 · 175 citations

, , +10

Biarylcarboxylic Acids and -amides:  Inhibition of Phosphodiesterase Type IV versus [<sup>3</sup>H]Rolipram Binding Activity and Their Relationship to Emetic Behavior in the Ferret

Allen J. Duplantier, Michael S. Biggers, Robert Chambers et al. · Journal of Medicinal Chemistry · 1996 · 143 citations · Full text

, , +16

High yields of unsymmetrical biaryls via cross coupling of arylboronic acids with haloarenes using a modified Suzuki-Beletskaya procedure

Eva M. Campi, W. Roy Jackson, Sebastian M. Marcuccio et al. · Journal of the Chemical Society Chemical Communications · 1994 · 84 citations

, , +15