Organocatalytic asymmetric synthesis of highly functionalized pyrrolizidines via cascade Michael/hemi-aminalization reactions of isoindolinones

Enamine-Based Organocatalysis with Proline and Diamines:  The Development of Direct Catalytic Asymmetric Aldol, Mannich, Michael, and Diels−Alder Reactions

Wolfgang Notz, Fujie Tanaka, Carlos F. Barbas · Accounts of Chemical Research · 2004 · 1.4K citations

Novel Organocatalysts, Bioorganic Chemistry, Engineering +15

Diphenylprolinol Silyl Ethers as Efficient Organocatalysts for the Asymmetric Michael Reaction of Aldehydes and Nitroalkenes

Yujiro Hayashi, Hiroaki Gotoh, Takaaki Hayashi et al. · Angewandte Chemie International Edition · 2005 · 1.2K citations

Chemical Engineering, Novel Organocatalysts, Engineering +14

Towards Organocatalytic Polyketide Synthases with Diverse Electrophile Scope: Trifluoroethyl Thioesters as Nucleophiles in Organocatalytic Michael Reactions and Beyond

Diego A. Alonso, Shinji Kitagaki, Naoto Utsumi et al. · Angewandte Chemie International Edition · 2008 · 111 citations

Novel Organocatalysts, Biosynthesis, Engineering +9

Structure-based drug design of a highly potent CDK1,2,4,6 inhibitor with novel macrocyclic quinoxalin-2-one structure

Nobuhiko Kawanishi, T Sugimoto, Jun Shibata et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 101 citations · Full text

Medicinal Chemistry, Medicine, Natural Sciences +10

Active Methylene Compounds in the Synthesis of 3-substituted Isobenzofuranones, Isoindolinones and Related Compounds

Antonia Di Mola, Laura Palombi, António Massa · Current Organic Chemistry · 2012 · 95 citations

Derivative (Chemistry), Isoindolinones Skeletons, Heterocyclic +10