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Digital droplet PCR‐based chimerism analysis for monitoring of hematopoietic engraftment after allogeneic stem cell transplantation

Thomas Mika, Alexander Baraniskin, Swedlana Ladigan, Gerald Wulf, Sascha Dierks, Detlef Haase, Karin Schork, Michael Turewicz, Martin Eisenacher, Wolff Schmiegel,

International Journal of Laboratory Hematology · 2019 · 28 citations · 20 references

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Abstract

According to our data, chimerism analysis by ddPCR has an excellent correlation with STR-based analyses. Due to its fast and easy applicability, the ddPCR technique is suitable for chimerism monitoring in clinical practice.

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20

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Monitoring of chimerism following allogeneic haematopoietic stem cell transplantation (<scp>HSCT</scp>): Technical recommendations for the use of Short Tandem Repeat (<scp>STR</scp>) based techniques, on behalf of the United Kingdom National External Quality Assessment Service for Leucocyte Immunophenotyping Chimerism Working Group

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Martin Bornhäuser, U. Oelschlaegel, Uwe Platzbecker et al. · Haematologica · 2009 · 111 citations · Full text