Digital PCR is a highly sensitive nucleic acid quantification method that belongs to the class of polymerase chain reaction techniques and is distinguished by its ability to detect and precisely measure rare genetic variants through partitioning of the sample into thousands of individual reactions, enabling absolute quantification without reliance on standard curves.
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Bert Vogelstein, Kenneth W. Kinzler · Proceedings of the National Academy of Sciences · 1999 · 1.7K citations
Rossa W. K. Chiu, K.C. Allen Chan, Yuan Gao et al. · Proceedings of the National Academy of Sciences · 2008 · 947 citations · Full text
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