Concepedia

Studies on Novel and Chiral 1,4-Dihydropyridines. I. Synthesis and Conformational Analysis of Novel NADH Model Compounds, N-Substituted (S)-3-(p-Tolylsulfinyl)-1,4-dihydropyridines.

Takeshi Imanishi, Satoshi Obika, Toshihiko Nishiyama, Masahiro Nishimoto, Y. HAMANO, Kazuyuki Miyashita, C. IWATA

Chemical and Pharmaceutical Bulletin · 1996 · 15 citations · 1 references

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Concepts

Abstract

Novel NADH model compounds, (SS)-1-alkyl-3-(p-tolylsulfinyl)-1, 4-dihydropyridines (2) and (RS)-1-benzyl-3-[1-oxo-2-(p-tolylsulfinyl)ethyl]-1, 4-dihydropyridine (3), were synthesized. 1H-NMR study and X-ray analysis of 2 revealed its preferred conformation.

References

1

<i>International Tables for X-ray Crystallography</i>

Acta Crystallographica Section B · 1976 · 14.2K citations · Full text

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